Abstract:
The aim of this work was to analyse mineral composition and chemical profile of two nonedible fungal species: Ganoderma lucidum and Ganoderma applanatum (Fruška Gora, Serbia) vs. their antioxidant (ABTS and A.E.A.C. assay) and cytotoxic biopotentials (MTT assay on MCF-7). Both species were analysed for their content of macro- and microelements by atomic absorption spectrophotometry, while phenolic profile of EtOH and H2O extracts was examined by LC-MS/MS technique. Both species mostly contained the following ions: K+ > Ca2+ > Mg2+ > Mn2+ > Zn2+ > Cu2+ > Cr3+. Among nine phenolic compounds, the highest content of vanillic acid was detected in G. applanatum extracts while protocatechuic acid in EtOH extract and quinic acid in H2O extract were mostly contained in G. lucidum. Ganoderma applanatum EtOH extract showed the best antioxidant activities related to its phenolic and flavonoid content. Further, the best cytotoxic effect after 72 h was observed in this extract as well.
