Mineral composition, antioxidant and cytotoxic biopotentials of wild‐growing Ganoderma species (Serbia): G. lucidum (Curtis) P. Karst vs. G. applanatum (Pers.) Pat.
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Date
2016-12
Authors
Rašeta, Milena
Karaman, Maja
Jakšić, Milena
Šibul, Filip
Kebert, Marko
Novaković, Aleksandra
Popović, Mira
Journal Title
Journal ISSN
Volume Title
Publisher
WILEY
Abstract
The aim of this work was to analyse mineral composition and chemical profile of two nonedible fungal species: Ganoderma lucidum and Ganoderma applanatum (Fruška Gora, Serbia) vs. their antioxidant (ABTS and A.E.A.C. assay) and cytotoxic biopotentials (MTT assay on MCF-7). Both species were analysed for their content of macro- and microelements by atomic absorption spectrophotometry, while phenolic profile of EtOH and H2O extracts was examined by LC-MS/MS technique. Both species mostly contained the following ions: K+ > Ca2+ > Mg2+ > Mn2+ > Zn2+ > Cu2+ > Cr3+. Among nine phenolic compounds, the highest content of vanillic acid was detected in G. applanatum extracts while protocatechuic acid in EtOH extract and quinic acid in H2O extract were mostly contained in G. lucidum. Ganoderma applanatum EtOH extract showed the best antioxidant activities related to its phenolic and flavonoid content. Further, the best cytotoxic effect after 72 h was observed in this extract as well.
Description
peer-reviewed
Keywords
antioxidant activity, cytotoxicity, ganoderma, LC-MS/MS, micronutrients, phenolic acids
Citation
M. Rašeta, M. Karaman, M. Jakšić, F. Šibul, M. Kebert, A. Novaković, M. Popović. Mineral composition, antioxidant and cytotoxic biopotentials of wild‐growing Ganoderma species (Serbia): G. lucidum (Curtis) P. Karst vs. G. applanatum (Pers.) Pat. International Journal of Food Science and Technology, 51 (2016) 2583–2590. DOI: 10.1111/ijfs.13243