Edible mycorrhizal species Lactarius controversus Pers. 1800 as a source of antioxidant and cytotoxic agents
| dc.contributor.advisor | ||
| dc.contributor.author | Novaković, Aleksandra | |
| dc.contributor.author | Karaman, Maja A. | |
| dc.contributor.author | Milovanović, Ivan | |
| dc.contributor.author | Belović, Miona | |
| dc.contributor.author | Rašeta, Milena M. | |
| dc.contributor.author | Radusin, Tanja | |
| dc.contributor.author | Ilić, Nebojša | |
| dc.date.accessioned | 2018-04-20T11:56:15Z | |
| dc.date.available | 2018-04-20T11:56:15Z | |
| dc.date.issued | 2016-03 | |
| dc.description | peer-reviewed | en_US |
| dc.description.abstract | The aim of this work was to study chemical profile and antioxidant and cytotoxic activities of ethanol and water extracts of Lactarius controversus (Pers.) 1800 mushroom species growing in eastern Serbia. The chemical characterization of phenolic compounds performed by HPLC-MS/MS demonstrated the presence of quinic acid among others. Determination of antioxidant activity, including radical scavenging effects on DPPH•, NO•, OH• and SOA radicals and ferric reducing ability was investigated. The highest DPPH radical scavenging effect was obtained for water extract (LcAq) while ethanol extract (LcEtOH) demonstrated the highest FRAP activity. Hexane extract applied in antibacterial assay against three pathogenic strains demonstrated antibacterial effect only against S. aureus ATCC25922. Anti-proliferative properties against estrogen dependent MCF 7 breast cancer cell lines using MTT showed higher activity for ethanolic extract. | en_US |
| dc.description.sponsorship | This paper is the result of research within the projects III 46001 and 172058, financed by the Ministry of Education, Science, and Technological Development, Republic of Serbia. The authors would like to thank Prof. Dr. Goran Anačkov for his valuable help in statistical analysis performance. | en_US |
| dc.identifier.citation | Novaković, A.R., Karaman, M.A., Milovanović, I.Lj., Belović, M.M., Rašeta, M.J., Radusin, T.I., Ilić, N.M. (2016) Edible mycorrhizal species Lactarius controversus Pers. 1800 as a source of antioxidant and cytotoxic agents. Hemijska industrija,70, 113–122. DOI: 10.2298/HEMIND141229017N | en_US |
| dc.identifier.issn | 0367-598X | |
| dc.identifier.uri | http://oa.fins.uns.ac.rs/handle/123456789/67 | |
| dc.language.iso | en | en_US |
| dc.publisher | Savez hemijskih inženjera Srbije | en_US |
| dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172058/RS// | |
| dc.relation | info:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/46001/RS// | |
| dc.relation.ispartofseries | 001;0062 | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | lactarius controversus | en_US |
| dc.subject | phenolic compounds | en_US |
| dc.subject | quinic acid | en_US |
| dc.subject | antioxidants | en_US |
| dc.subject | cytotoxic agents | en_US |
| dc.title | Edible mycorrhizal species Lactarius controversus Pers. 1800 as a source of antioxidant and cytotoxic agents | en_US |
| dc.title.alternative | - | en_US |
| dc.type | info:eu-repo/semantics/article | en_US |