Edible mycorrhizal species Lactarius controversus Pers. 1800 as a source of antioxidant and cytotoxic agents

Novaković, Aleksandra; Karaman, Maja A.; Milovanović, Ivan; Belović, Miona; Rašeta, Milena M.; Radusin, Tanja; Ilić, Nebojša

dc.contributor.advisor
dc.contributor.author	Novaković, Aleksandra
dc.contributor.author	Karaman, Maja A.
dc.contributor.author	Milovanović, Ivan
dc.contributor.author	Belović, Miona
dc.contributor.author	Rašeta, Milena M.
dc.contributor.author	Radusin, Tanja
dc.contributor.author	Ilić, Nebojša
dc.date.accessioned	2018-04-20T11:56:15Z
dc.date.available	2018-04-20T11:56:15Z
dc.date.issued	2016-03
dc.identifier.citation	Novaković, A.R., Karaman, M.A., Milovanović, I.Lj., Belović, M.M., Rašeta, M.J., Radusin, T.I., Ilić, N.M. (2016) Edible mycorrhizal species Lactarius controversus Pers. 1800 as a source of antioxidant and cytotoxic agents. Hemijska industrija,70, 113–122. DOI: 10.2298/HEMIND141229017N	en_US
dc.identifier.issn	0367-598X
dc.identifier.uri	http://oa.fins.uns.ac.rs/handle/123456789/67
dc.description	peer-reviewed	en_US
dc.description.abstract	The aim of this work was to study chemical profile and antioxidant and cytotoxic activities of ethanol and water extracts of Lactarius controversus (Pers.) 1800 mushroom species growing in eastern Serbia. The chemical characterization of phenolic compounds performed by HPLC-MS/MS demonstrated the presence of quinic acid among others. Determination of antioxidant activity, including radical scavenging effects on DPPH•, NO•, OH• and SOA radicals and ferric reducing ability was investigated. The highest DPPH radical scavenging effect was obtained for water extract (LcAq) while ethanol extract (LcEtOH) demonstrated the highest FRAP activity. Hexane extract applied in antibacterial assay against three pathogenic strains demonstrated antibacterial effect only against S. aureus ATCC25922. Anti-proliferative properties against estrogen dependent MCF 7 breast cancer cell lines using MTT showed higher activity for ethanolic extract.	en_US
dc.description.sponsorship	This paper is the result of research within the projects III 46001 and 172058, financed by the Ministry of Education, Science, and Technological Development, Republic of Serbia. The authors would like to thank Prof. Dr. Goran Anačkov for his valuable help in statistical analysis performance.	en_US
dc.language.iso	en	en_US
dc.publisher	Savez hemijskih inženjera Srbije	en_US
dc.relation	info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172058/RS//
dc.relation	info:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/46001/RS//
dc.relation.ispartofseries	001;0062
dc.rights	info:eu-repo/semantics/openAccess
dc.subject	lactarius controversus	en_US
dc.subject	phenolic compounds	en_US
dc.subject	quinic acid	en_US
dc.subject	antioxidants	en_US
dc.subject	cytotoxic agents	en_US
dc.title	Edible mycorrhizal species Lactarius controversus Pers. 1800 as a source of antioxidant and cytotoxic agents	en_US
dc.title.alternative	-	en_US
dc.type	info:eu-repo/semantics/article	en_US