Influence of Artemisia absinthium essential oil on antioxidative system of broilers experimentally infected with Eimeria oocysts

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dc.contributor.authorKostadinović, Ljiljana
dc.contributor.authorPopović, Sanja
dc.contributor.authorPuvača, Nikola M.
dc.contributor.authorČabarkapa, Ivana
dc.contributor.authorKormanjoš, Šandor M.
dc.contributor.authorLević, Jovanka
dc.date.accessioned2018-04-18T13:58:54Z
dc.date.available2018-04-18T13:58:54Z
dc.date.issued2016-03
dc.descriptionpeer-revieweden_US
dc.description.abstractThe aim of this study was to investigate the effects of Artemisia absinthium essential oil (AAEO) on the enzymatic activity of superoxide-dismutase (SOD), glutathione-peroxidase (GSHPx), glutathione-reductase (GR), peroxidase (POD) and xanthine-oxidase (XOD) and the content of lipid peroxides (LPx) and glutathione (GSH) in broilers infected with an oocyst mixture of Eimeria tenella, Eimeria mitis and Eimeria necatrix, compared to coccidicide salinomycine. The investigation was carried out on 240 Arbour acres broilers of both sexes. Broilers were distributed completely randomly into four treatment groups: treatment group A was uninfected and untreated; treatment group B was infected and kept untreated; treatment group C preventively received coccidicide salinomycine in a dose of 60 mg/kg of feed and inoculated with an oocyst mixture on the 21st day-of-age; treatment group D received AAEO in their feed in a dose of 3 g/kg and were infected with the oocyst mixture on the 21st day of age. During the study, bloody diarrhoea was observed from the 3rd to 9th day after the challenge. After six days of infection, the most intensive bloody diarrhoea was noticed in the un-medicated treatment group. In order to evaluate the effects of essential oil on poultry coccidiosis induced by Eimeria spp., oocysts per gram of faeces (OPG) were also investigated in all treatment groups. During the experiment, the oocyst output and mortality rate were significantly lower (P<0.05) in the AAEO treatment group (D-2) in comparison to the positive control (B), while significant excretion of oocysts was noticed in the faeces of non-treated broilers infected with Eimeria spp. The broilers treated with salinomycin (C-2) showed complete reduction of oocysts in their faeces at 30 days of age. The results obtained in this study indicate changes in the content and the activity of the non-enzymatic and enzymatic antioxidative protective systems in blood hemolysates of infected chickens. The positive preventive effects of AAEO, applied in a concentration of 3g/kg of feed, were high on the antioxidative system of erythrocytes. On the basis of the obtained results, it was concluded that AAEO was effective in lowering the intensity of bloody diarrhoea, as well in reducing the oocyst output of the preventively treated and infected broilers; hence it may be used as a prophylactic feed additive. Moreover, AAEO showed an important role in the activation of antioxidative protection systems in infected broilers, which is of great interest since free radicals and lipid peroxides, formed as a result of lower food intake and exhaustion of the organism induced by diarrhoea, could cause cellular membrane damage.en_US
dc.description.sponsorshipThe paper is a part of the research work on the project III 46012 financed by the Ministry of Education, Science and Technological Development of the Republic of Serbia.en_US
dc.identifier.citationKostadinović, Lj., Popović, S., Puvača, N., Čabarkapa, I., Kormanjoš, Š., Lević, J. (2016) Influence of Artemisia absinthium essential oil on antioxidative system of broilers experimentally infected with Eimeria oocysts. Veterinarski arhiv, 86, 253–264.en_US
dc.identifier.issn0372-5480
dc.identifier.urihttp://oa.fins.uns.ac.rs/handle/123456789/61
dc.language.isoenen_US
dc.publisherFaculty of Veterinary Medicine University of Zagreben_US
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/46012/RS//
dc.relation.ispartofseries001;0056
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectartemisia absinthiumen_US
dc.subjectcoccidiosisen_US
dc.subjectprophylactic feed additiveen_US
dc.subjectantioxidative systemen_US
dc.subjectsalinomycinen_US
dc.titleInfluence of Artemisia absinthium essential oil on antioxidative system of broilers experimentally infected with Eimeria oocystsen_US
dc.title.alternative-en_US
dc.typeinfo:eu-repo/semantics/articleen_US

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