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Edible mycorrhizal species Lactarius controversus Pers. 1800 as a source of antioxidant and cytotoxic agents

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dc.contributor.advisor
dc.contributor.author Novaković, Aleksandra
dc.contributor.author Karaman, Maja A.
dc.contributor.author Milovanović, Ivan
dc.contributor.author Belović, Miona
dc.contributor.author Rašeta, Milena M.
dc.contributor.author Radusin, Tanja
dc.contributor.author Ilić, Nebojša
dc.date.accessioned 2018-04-20T11:56:15Z
dc.date.available 2018-04-20T11:56:15Z
dc.date.issued 2016-03
dc.identifier.citation Novaković, A.R., Karaman, M.A., Milovanović, I.Lj., Belović, M.M., Rašeta, M.J., Radusin, T.I., Ilić, N.M. (2016) Edible mycorrhizal species Lactarius controversus Pers. 1800 as a source of antioxidant and cytotoxic agents. Hemijska industrija,70, 113–122. DOI: 10.2298/HEMIND141229017N en_US
dc.identifier.issn 0367-598X
dc.identifier.uri http://oa.fins.uns.ac.rs/handle/123456789/67
dc.description peer-reviewed en_US
dc.description.abstract The aim of this work was to study chemical profile and antioxidant and cytotoxic activities of ethanol and water extracts of Lactarius controversus (Pers.) 1800 mushroom species growing in eastern Serbia. The chemical characterization of phenolic compounds performed by HPLC-MS/MS demonstrated the presence of quinic acid among others. Determination of antioxidant activity, including radical scavenging effects on DPPH•, NO•, OH• and SOA radicals and ferric reducing ability was investigated. The highest DPPH radical scavenging effect was obtained for water extract (LcAq) while ethanol extract (LcEtOH) demonstrated the highest FRAP activity. Hexane extract applied in antibacterial assay against three pathogenic strains demonstrated antibacterial effect only against S. aureus ATCC25922. Anti-proliferative properties against estrogen dependent MCF 7 breast cancer cell lines using MTT showed higher activity for ethanolic extract. en_US
dc.description.sponsorship This paper is the result of research within the projects III 46001 and 172058, financed by the Ministry of Education, Science, and Technological Development, Republic of Serbia. The authors would like to thank Prof. Dr. Goran Anačkov for his valuable help in statistical analysis performance. en_US
dc.language.iso en en_US
dc.publisher Savez hemijskih inženjera Srbije en_US
dc.relation info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172058/RS//
dc.relation info:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/46001/RS//
dc.relation.ispartofseries 001;0062
dc.rights info:eu-repo/semantics/openAccess
dc.subject lactarius controversus en_US
dc.subject phenolic compounds en_US
dc.subject quinic acid en_US
dc.subject antioxidants en_US
dc.subject cytotoxic agents en_US
dc.title Edible mycorrhizal species Lactarius controversus Pers. 1800 as a source of antioxidant and cytotoxic agents en_US
dc.title.alternative - en_US
dc.type info:eu-repo/semantics/article en_US


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