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The Application of Ultrasonic Waves and Microwaves to Improve Antihyperglycaemic and Antimicrobial Activities of Marrubium vulgare Extracts

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dc.contributor.author Gavarić, Aleksandra
dc.contributor.author Vladić, Jelena
dc.contributor.author Vujetić, Jelena
dc.contributor.author Radnović, Dragan
dc.contributor.author Volarić, Ana
dc.contributor.author Živković, Jelena
dc.contributor.author Šavikin, Katarina
dc.contributor.author Vidović, Senka
dc.date.accessioned 2023-07-17T07:30:31Z
dc.date.available 2023-07-17T07:30:31Z
dc.date.issued 2022-10-25
dc.identifier.issn 2079-6382
dc.identifier.uri http://oa.fins.uns.ac.rs/handle/123456789/290
dc.description.abstract Having scarce information about ultrasound assisted extraction (UAE) and microwave assisted extraction (MAE) of white horehound (Marrubium vulgare L.), the idea has emerged to determine the optimal process parameters for the maximization of polyphenols and to compare the efficiency of these green extraction technologies. The optimal UAE parameters are temperature of 73.6 ◦C, extraction time of 40 min and ultrasound power of 30.3 W/L, while the optimal MAE parameters are 63.8% ethanol, extraction time of 15 min and microwave power of 422 W. Extract obtained at optimal UAE parameters shows the highest antihyperglycemic activity (α-amylase inhibition: 50.63% and α-glucosidase inhibition: 48.67%), which can potentially be explained by the presence of chlorogenic acid and quercetin, which were not identified in the macerates. The most sensitive bacterial strain to optimal ultrasonic extract is Bacillus cereus, whereas the most sensitive fungal strain is Saccharomyces cerevisiae. en_US
dc.description.sponsorship This research was funded by the Program of Ministry of Education, Science and Technolog ical Development of Republic of Serbia; Projects No. 451-03-68/2022-14/200134 and No. 451-03-68/ 2022-14/200125. en_US
dc.language.iso en en_US
dc.publisher MDPI en_US
dc.relation eu-repo/grantAgreement/MESTD/inst-2020/200222/RS//
dc.rights OpenAccess
dc.subject Marrubium vulgare en_US
dc.subject ultrasound extraction en_US
dc.subject microwave extraction en_US
dc.subject antihyperglycaemic activity en_US
dc.subject antimicrobial activity en_US
dc.title The Application of Ultrasonic Waves and Microwaves to Improve Antihyperglycaemic and Antimicrobial Activities of Marrubium vulgare Extracts en_US
dc.type Article en_US
dc.type info:eu-repo/semantics/article
dc.identifier.scopus 2-s2.0-85141814447
dc.identifier.wos 000883353400001
dc.identifier.doi 10.3390/antibiotics11111475


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