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Tomato waste: Carotenoids content, antioxidant and cell growth activities

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dc.contributor.author Stajčić, Slađana
dc.contributor.author Ćetković, Gordana
dc.contributor.author Čanadanović-Brunet, Jasna
dc.contributor.author Đilas, Sonja
dc.contributor.author Mandić, Anamarija
dc.contributor.author Četojević-Simin, Dragana
dc.date.accessioned 2017-04-27T09:12:16Z
dc.date.available 2017-04-27T09:12:16Z
dc.date.issued 2015-04-01
dc.identifier.citation S. Stajčić, G. Ćetković, J. Čanadanović-Brunet, S. Đjilas, A. Mandić, D. Četojević-Simin. Tomato waste: Carotenoids content, antioxidant and cell growth activities. Food Chemistry 172 (2015) 225–232. DOI: 10.1016/j.foodchem.2014.09.069 en_US
dc.identifier.issn 0308-8146
dc.identifier.uri http://oa.fins.uns.ac.rs/handle/123456789/20
dc.description peer-reviewed en_US
dc.description.abstract The carotenoid content, antioxidant and cell growth activities of tomato waste extracts, obtained from five different tomato genotypes, was investigated. High performance liquid chromatography was used to identify and quantify the main carotenoids present in tomato waste extracts. The antioxidant activity of tomato waste extracts was tested using spectrophotometric methods, 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity and reducing power assay. The highest DPPH scavenging activity (IC50 = 0.057 mg/ml) was obtained for Bačka extract. The Knjaz extract showed the best reducing power (IC50 = 2.12 mg/ml). Cell growth effects were determined in HeLa, MCF7 and MRC-5 cell lines by sulforhodamine B test. Anti-proliferative effects were observed in all cell lines at higher concentrations (⩾0.125 mg/ml). The carotenoid contents exhibited a strong correlation with antioxidant and anti-proliferation activity. The results obtained indicated that tomato waste should be regarded as potential nutraceutic resource and may be used as a functional food ingredient. en_US
dc.description.sponsorship This paper is a result of the research within the project TR 31044 financed by the Ministry of Education, Science and Technological Development, Republic of Serbia. en_US
dc.language.iso en en_US
dc.publisher Elsevier en_US
dc.relation info:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/31044/RS//
dc.relation.ispartofseries 1;0016
dc.rights info:eu-repo/semantics/openAccess
dc.subject tomato waste en_US
dc.subject carotenoids en_US
dc.subject HPLC/DAD en_US
dc.subject reducing power en_US
dc.subject DPPH assay en_US
dc.subject cell growth activity en_US
dc.title Tomato waste: Carotenoids content, antioxidant and cell growth activities en_US
dc.title.alternative - en_US
dc.type info:eu-repo/semantics/article en_US


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